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Scop: Cercetarea riscului cardiovascular la pacienţii cu nefropatie diabetică, utilizând drept indicator grosimea intimă medie carotidiană. Materiale si metode: Studiul a fost efectuat pe un grup de 60 de pacienţi 41 bărbaţi şi 19 femei cu diabet zaharat, dintre care: 20 fără nefropatie diabetică lotul martor21 cu nefropatie diabetică incipientă şi 19 cu nefropatie diabetică clinic manifestă.

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Toţi pacienţii luaţi în studiu au fost asimptomatici din punct de vedere cardiovascular. Cercetarea riscului cardiovascular la pacienţii cu nefropatie diabetică a fost efectuată neinvaziv, prin determinarea grosimii intimei mediei de la nivelul arterei carotide comune cu ajutorul ecografului ALOKA ProSound SSDcu sondă liniară de 10 MHz.

Cuvinte cheie: risc cardiovascular, nefropatie diabetica, grosimea intimă medie carotidiană. Aim: The research of cardiovascular risk in patients with diabetic nephropathy, using as indicator the thickness of intima-medium of the 2 6 common carotid artery.

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Materials and methods: The study was conducted on a group of 60 patients 41 men and 19 women with diabetes, of which: 20 without diabetic nephropathy control group21 with early diabetic nephropathy and 19 with clinically manifest diabetic nephropathy. All patients that we used for the study were asymptomatic from the cardiovascular point of view.

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The research of the cardiovascular risk in patients with diabetic nephropathy was made non-invasively by determining the thickness of the intima - medium of common carotid artery using ultrasound ALOKA ProSound SSD10 MHz linear probe. Results: In diabetics patients without diabetic nephropathy, this index value was 0. The thickness of the intima - medium of common carotid artery had higher values in clinically manifest diabetic nephropathy 1.

Starting with an early stage diabetic nephropathy, cardiovascular risk begins to increase, cardiovascular disease being the main cause of morbidity and mortality in patients with diabetic nephropathy [1,13,14].

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Heart diseases in diabetic chronic renal disease is the result of action of many cardiovascular risk factors: some related to diabetes, and others associated to chronic nephropathy. The research of cardiovascular risk in patients with diabetic nephropathy, is made by using the thickness of the intima - medium of common carotid artery [,7]. Among major risk factors, hypertension has the can hpv virus cause ms effect on the thickness of the intima - medium of common carotid artery, probably due to media hypertrophy, which is a specific process of clinico diphyllobothriasis imagine remodeling [21].

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Age, overweight, increased cholesterol, diabetes, smoking it is positively associated with the thickness of the intima - medium of common carotid artery level [15]. The mean age of patients was ± years.

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All patients taking the study were asymptomatic from the cardiovascular point of view. The research of the thickness of the intima - medium of common carotid artery was made in 20 patients with diabetes mellitus and diabetic nephropathy, clinico diphyllobothriasis imagine a mean age of ± years, and the duration of disease progression ± 8.

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Table 1. Normally, the carotid wall thickness is less than 0.

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Table 3. Table 4.

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At diabetic patients without diabetic nephropathy, this index value was 0. The thickness of the intima-medium clinico diphyllobothriasis imagine carotid artery had higher values in clinically manifested diabetic nephropathy 1.

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Diabetes Care, 27 Suppl. Anavekar N.

Kidney Int Suppl, S50 S55 3. Atkins R.

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Am J Cardiol, 90 suppl : 40L 48L 5. Breyer J.

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P, Evans J. Cardiovascular risk is still present in the early stage of diabetic nephropathy, and increases with the severity of diabetic renal disease.

Cardiovascular risk increases with the degree of the proteinuria. The presence of the microalbuminuria or proteinuria requires identification of all cardiovascular risk factors, in the therapeutic interventions for their correction [25].